FGF21 response

There is 1 paper on FGF21 response in aging research: none in people yet, 1 in animals.

Biomarker

1 paper studies it10 more mention it3 findings

See all 11 papers on FGF21 response

“Individuals exhibiting delayed glycemic improvement (responders) displayed a significantly stronger FGF21 response than non-responders.”
Influence of Fibroblast Growth Factor 21 on Delayed Glycemic Improvement Following Acute Exercise in Type 2 Diabetes MellitusDiabetes & metabolism journal2026doi:10.4093/dmj.2024.0814
  • Animals1

Associations

3

Baseline metabolites

mixedin humans1

1 study
  1. Baseline metabolites are associated with FGF21 response in humans (baseline, before exercise).

    “Baseline metabolites, including p-cresol sulfate and dimethylglycine, differed between responders and non-responders and were associated with the FGF21 response.”

    Human trialbaseline, before exercise

    Influence of Fibroblast Growth Factor 21 on Delayed Glycemic Improvement Following Acute Exercise in Type 2 Diabetes Mellitus

    Diabetes & metabolism journal

More on Baseline metabolites

Delayed glycemic improvement

upin humans1

1 study
  1. FGF21 response is associated with delayed glycemic improvement in humans after acute exercise, responders vs non-responders.

    “Individuals exhibiting delayed glycemic improvement (responders) displayed a significantly stronger FGF21 response than non-responders.”

    Human trialafter acute exercise, responders vs non-responders

    Influence of Fibroblast Growth Factor 21 on Delayed Glycemic Improvement Following Acute Exercise in Type 2 Diabetes Mellitus

    Diabetes & metabolism journal

NUPR1

mixedin mice1

1 study
  1. NUPR1 is associated with FGF21 response in mice.

    “Both the FGF21 suppression by exercise and potentiation by repeated cycles correlated tightly with Nupr1 mRNA in liver”

    Animalsliver

    Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements

    Molecular metabolism

More on NUPR1

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 2Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 03 papers in 12 months

See all 11 papers on FGF21 response