Fasting blood metabolomic risk score

1. Fasting blood metabolomic risk score raises the risk of coronary heart disease in humans (RR 1.48 (95% CI: 1.04, 2.12)).

   “and 1.48 (1.04, 2.12) for CHD compared to those in the lowest 20%.”

   Humanstop 20% vs lowest 20% of MRS, multivariate-adjustedfemales

   Blood Metabolomic Atlas for One-Hour Post-Load Glucose Predicts Long-Term Glycemic Dynamics and Cardiometabolic Disease Incidence

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

More on Coronary heart disease

1. Fasting blood metabolomic risk score raises the risk of type 2 diabetes in humans (RR 3.80 (95% CI: 2.22, 6.51)).

   “women in the top 20% of MRS had a multivariate-adjusted relative risk of 3.80 (95% CI: 2.22, 6.51) for T2D”

   Humanstop 20% vs lowest 20% of MRS, multivariate-adjustedfemales

   Blood Metabolomic Atlas for One-Hour Post-Load Glucose Predicts Long-Term Glycemic Dynamics and Cardiometabolic Disease Incidence

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

More on Type 2 diabetes

1. Fasting blood metabolomic risk score predicts 1-hour glucose in humans (r = 0.8).

   “We developed a fasting blood MRS for predicting 1-hour glucose levels (Pearson r = 0.8) using a machine-learning elastic net regression model.”

   Human trialpredicting 1-hour glucose levels

   Blood Metabolomic Atlas for One-Hour Post-Load Glucose Predicts Long-Term Glycemic Dynamics and Cardiometabolic Disease Incidence

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

More on 1-hour glucose