Fast-activating Kv3 current

Fast-activating Kv3 current increases intrinsic lateral olivocochlear neuron firing rate in mice.

“In ageing animals, and distinct from post-natal development, further increased firing rates were supported by an increased size of the fast-activating Kv3 current.”

Animalswild-type miceintrinsic lateral olivocochlear neuron

Kv4, Kv2, and Kv3 currents shape intrinsic lateral olivocochlear excitability independent of hair cell dysfunction during development and ageing

bioRxiv (Cold Spring Harbor Laboratory)·Jul 3, 2026Preprint