Facial skin aging

1. Facial skin aging has no effect on osteoporosis in silico.

   “FSA was not genetically associated as well as causally associated with all studied osteoporosis-related traits.”

   In silicogenetic and Mendelian randomization analyses

   Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies

   Journal of bone and mineral metabolism·5 Nov 2025

More on Osteoporosis

1. Facial skin aging is associated with fractures in humans (HR = 1.501, p < 0.001).

   “FSA was positively associated with the risks of osteoporosis (HR = 1.852, p < 0.001) and fracture (HR = 1.501, p < 0.001).”

   Humansobservational analysis

   Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies

   Journal of bone and mineral metabolism·5 Nov 2025

More on Fractures

1. Facial skin aging is associated with osteoporosis in humans (HR = 1.852, p < 0.001).

   “FSA was positively associated with the risks of osteoporosis (HR = 1.852, p < 0.001)”

   Humansobservational analysis

   Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies

   Journal of bone and mineral metabolism·5 Nov 2025

More on Osteoporosis

1. Facial skin aging is associated with estimated bone mineral density in humans (p < 0.001).

   “Higher degrees of FSA were associated with lower eBMD (p < 0.001)”

   Humansobservational analysis

   Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies

   Journal of bone and mineral metabolism·5 Nov 2025

More on Estimated bone mineral density