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Estimated left ventricular filling pressures

Biomarker

1 paper studies it1 finding

  • Human trial1

Interventions

1

Ketone ester

downin humans1

1 study

  1. Ketone ester decreases estimated left ventricular filling pressures in humans.

    “During both exercise protocols, KE lowered: 1) respiratory exchange ratios, demonstrating decreased systemic carbohydrate use; 2) nonesterified fatty acids and glucose; and 3) estimated left ventricular filling pressures (E/e').”

    Human trialsymptomatic HFpEF during exerciseketone estern = 20

    Crossover Trial of Exogenous Ketones on Cardiometabolic Endpoints in Heart Failure With Preserved Ejection Fraction

    JACC. Heart failure

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