Epigenetic aging measures

Biomarker1 paper2 findings

  • Humans1

Effects

1

Cognitive function

no changein humans1

1 study
  1. Epigenetic aging measures have no effect on cognitive function in humans.

    Humanswithin-person change after FDR correction

    Epigenetic Aging Clocks Associate with Cognitive Status More Strongly Than Short-Term Cognitive Change: Evidence from the Parkinson's Progression Markers Initiative · Dementia and geriatric cognitive disorders · 1 Sep 2026

Associations

1

Cognitive function

downin humans1

1 study
  1. Epigenetic aging measures are associated with cognitive function in humans.

    Humansin PPMI cohort

    Epigenetic Aging Clocks Associate with Cognitive Status More Strongly Than Short-Term Cognitive Change: Evidence from the Parkinson's Progression Markers Initiative · Dementia and geriatric cognitive disorders · 1 Sep 2026

Latest

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Neurology Open AccessHumans

Epigenetic age links to higher dementia risk in older adults

In 2,606 participants, higher DunedinPACE was associated with increased risks of mild cognitive impairment (hazard ratio 1.16) and all-cause dementia…In 2,606 participants, higher DunedinPACE was associated with increased risks of mild cognitive impairment (hazard ratio 1.16) and all-cause dementia (hazard ratio 1.30).