Genome Medicine
Genetic scores better predict coronary artery disease in China
In training, a statistical performance measure rose approximately 60% versus the best East Asian-specific score and 90% versus the best European-specific score.In training, a statistical performance measure rose approximately 60% versus the best East Asian-specific score and 90% versus the best European-specific score.
Case-control studyCoronary artery disease
Who was studiedChinese coronary artery disease cases and controls
What changedIn the Chinese training group, combined-ancestry scores improved model fit by approximately 60% against the best East Asian-specific scores
The catchThe improvement measures training-set model fit, a stand-in for prediction in new patients