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DRD2 change

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Body mass index

upin humans1

1 study

  1. Body mass index is associated with DRD2 change in humans (r = 0.23).

    “lower BMI at baseline were associated with faster 5-year DRD2 decline in the putamen (r = -0.17, p < 0.05) and caudate (r = 0.23, p < 0.05), respectively.”

    Humanslower baseline BMI associated with faster declinecaudate5 years

    Cerebral small-vessel disease severity, hypertension, and body mass index forecast striatal dopamine D2-receptor decline rates in aging

    Neurobiology of aging6 Aug 2025

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Systolic blood pressure

downin humans1

1 study

  1. Systolic blood pressure is associated with DRD2 change in humans (r = −0.17).

    “Higher systolic blood pressure and lower BMI at baseline were associated with faster 5-year DRD2 decline in the putamen (r = -0.17, p < 0.05)”

    Humanshigher systolic blood pressure at baselineputamen5 years

    Cerebral small-vessel disease severity, hypertension, and body mass index forecast striatal dopamine D2-receptor decline rates in aging

    Neurobiology of aging6 Aug 2025

More on Systolic blood pressure

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