DNA methylation marker of smoking pack years

DNA methylation marker of smoking pack years are associated with frontal lobe volume in humans.

“driven by the association of a DNA methylation marker of smoking pack years with frontal and temporal lobe volumes.”

Humansfrontal lobe8 yearsfemalesn = 1,196

Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer's disease neurodegeneration

medRxiv : the preprint server for health sciences·26 Jan 2026Preprint