DAT extreme-deviation burden
Biomarker1 paper1 finding
- Humans1
Upstream
1Intermediate amyloid burden
upin humans1
1 study
Intermediate amyloid burden
upin humans1
Intermediate amyloid burden increases DAT extreme-deviation burden in humans (difference = 0.032, q = 0.044).
Humanscognitively unimpaired with intermediate amyloid burden (10 <= CL < 30) vs amyloid-positive (CL >= 30)
Normative brain models reveal dopamine shifts in early amyloid · bioRxiv · 29 Sep 2026 · Preprint
Latest
1bioRxivHumansPreprint
Normative brain models reveal dopamine shifts in early amyloid
In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status…In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted difference of −0.582.