DAF-16/FOXO activation
1 paper
- Model organisms1
Latest
Frontiers in Pharmacology
20(S)-protopanaxadiol prolongs lifespan and enhances stress resistance in Caenorhabditis elegans via the insulin/IGF-1 signaling pathway
Experiments in wormsInterventions
Nature Communications
DOS-3 mediates cell-non-autonomous DAF-16/FOXO activity in antagonizing age-related loss of C. elegans germline stem/progenitor cells
Experiments in wormsFOXO signalling
eLife
Mitochondrial stress in GABAergic neurons non-cell autonomously regulates organismal health and aging
Preprint: experiments in wormsMitochondrion
eLife
Mitochondrial stress in GABAergic neurons non-cell autonomously regulates organismal health and aging
Preprint: experiments in wormsMitochondrion
bioRxiv
Mitochondrial stress in GABAergic neurons non-cell autonomously regulates organismal health and aging
Preprint: experiments in wormsMitochondrion
Science Advances
Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations
Experiments in wormsFOXO signalling
bioRxiv
Conserved neuropeptidergic regulation of intestinal integrity in invertebrate models of aging
Preprint: experiments in wormsGut and microbiome
bioRxiv
ZIP-5/bZIP transcription factor regulation of folate metabolism is critical for aging axon regeneration
Preprint: experiments in animalsInterventions
Current Biology
Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress
Experiments in model organismsMechanisms
bioRxiv
Intergenerational effects of dietary restriction on insulin/IGF signaling and reproductive development
Preprint: experiments in model organismsInterventions