Cumulative estimated glucose disposal rate

1. Cumulative estimated glucose disposal rate is associated with incident frailty in humans.

   “increases in cumulative eGDR and in changes in eGDR over time were associated with lower risks of incident frailty and frailty index.”

   HumansHigher cumulative eGDRbaseline to the most recent survey wave

   Estimated glucose disposal rate and frailty in middle and older aged adults from three prospective cohorts

   Scientific reports·9 Dec 2025

1. Cumulative estimated glucose disposal rate is associated with cardiovascular disease in humans (p for trend <0.001).

   “A stepwise increase of outcomes was observed with the increased cumulative eGDR (p for trend <0.001).”

   Humansstepwise increase with increased cumulative eGDR4.42 years mean follow-upn = 2,895

   Association between the changes in the estimated glucose disposal rate and new-onset cardiovascular disease in middle-aged and elderly individuals: A nationwide prospective cohort study in China

   Diabetes, obesity & metabolism·6 Jan 2025

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