Cumulative C-reactive protein-triglyceride-glucose index

Biomarker

3 papers4 findings

  • Humans3

Associations

4

Stroke

upin humans1HR 1.15

1 study
  1. Cumulative C-reactive protein-triglyceride-glucose index raises the risk of stroke in humans (HR=1.15, 95% CI:1.03-1.29).

    “dyslipidemia (HR=1.80, 95% CI:1.69-1.92), stroke (HR=1.15, 95% CI:1.03-1.29), and asthma (HR=1.25, 95% CI:1.08-1.45)”

    Humansin CHARLS

    Association between C-Reactive Protein–Triglyceride–Glucose Index and New-Onset Chronic Disease Incidence and Mortality: Evidence from Multinational Cohorts

    ADA Scientific Sessions 2026 abstract5 Jun 2026

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Diabetes

upin humans1HR 1.6

1 study
  1. Cumulative C-reactive protein-triglyceride-glucose index raises the risk of diabetes in humans (HR=1.60, 95% CI:1.47-1.74).

    “In CHARLS, higher cumCTI increased risks of hypertension (HR=1.18, 95% CI:1.11-1.26), diabetes (HR=1.60, 95% CI:1.47-1.74)”

    Humansin CHARLS

    Association between C-Reactive Protein–Triglyceride–Glucose Index and New-Onset Chronic Disease Incidence and Mortality: Evidence from Multinational Cohorts

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on Diabetes

Cardiometabolic multimorbidity

upin humans1HR 1.02

1 study
  1. Cumulative C-reactive protein-triglyceride-glucose index raises the risk of cardiometabolic multimorbidity in humans (HR = 1.02, 95% CI 1.00-1.05).

    “each 1-unit increase in cumulative CTI was associated with an HR of 1.02 (95% CI 1.00-1.05)”

    HumansCHARLS 2015 baseline subcohort

    The association of C-reactive protein-triglyceride-glucose index with cardiometabolic multimorbidity in middle-aged and older adults: evidence from two cohort studies

    Cardiovascular diabetology13 Feb 2026

More on Cardiometabolic multimorbidity

Frailty

upin humans1HR 1.14

1 study
  1. Cumulative C-reactive protein-triglyceride-glucose index raises the risk of frailty in humans (HR 1.14, 95% CI 1.09-1.19).

    “each additional unit of cumCTI was linked to a 14% escalation in frailty risk (HR, 1.14; 95% CI, 1.09-1.19).”

    Humans

    Association between different dimensions of C-reactive protein-triglyceride-glucose index and the incidence of frailty in middle-aged and elderly adults in China: a nationwide prospective cohort study

    Lipids in health and disease19 Jan 2026

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