Combined Naples Prognostic Score and PhenoAge acceleration

Combined Naples Prognostic Score and PhenoAge acceleration improves predictive performance for poor functional outcomes in humans.

“Incorporating combined NPS and PAA into the basic model improved predictive performance for short- and long-term poor functional outcomes.”

HumansAddition to the basic model in patients with acute ischemic stroke or transient ischemic attack3 months and 1 yearn = 7,932

Association of the Naples Prognostic Score With Functional Outcomes and the Mediating Effects of PhenoAge Acceleration in Patients With Acute Ischemic Stroke or Transient Ischemic Attack: A Nationwide Registry Study

Journal of the American Heart Association·30 Jan 2026

Combined Naples Prognostic Score and PhenoAge acceleration is associated with poor functional outcomes in humans (Adjusted OR 2.16, 95% CI 1.73–2.70).

“Patients with both high NPS and PAA ≥0 had the highest risks of poor outcomes (adjusted OR, 2.16 [95% CI, 1.73-2.70] for mRS 3-6;”

HumansAcute ischemic stroke or transient ischemic attack; high NPS and PhenoAge acceleration ≥03 monthsn = 7,932

Association of the Naples Prognostic Score With Functional Outcomes and the Mediating Effects of PhenoAge Acceleration in Patients With Acute Ischemic Stroke or Transient Ischemic Attack: A Nationwide Registry Study

Journal of the American Heart Association·30 Jan 2026