Collagen VII

1. Rapamycin increases collagen VII in humans (P = 0.0077).

   “A significant (P = 0.008) reduction in p16INK4A protein levels and an increase in collagen VII protein levels (P = 0.0077) were observed among participants at the end of the study.”

   Human trialphotoaging and dermal volume losstopicalskin

   Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial

   GeroScience·25 Nov 2019

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