Cognitive dispersion

1. Alzheimer's disease biomarkers are associated with cognitive dispersion in humans.

   “increasing AD biomarker burden was related to increasing cognitive dispersion among individuals with cognitive impairment but not among cognitively unimpaired individuals”

   Humansamong individuals with cognitive impairment

   Developing and validating normed scores for cognitive dispersion among older adults

   AAIC 2025 abstract·25 Dec 2025

More on Alzheimer's disease biomarkers

1. Cognitive dispersion predicts Lewy body disease in humans (AUC range = .81-.88).

   “Cognitive dispersion scores differentiated individuals with cognitive impairment due to Lewy body disease from cognitively unimpaired individuals with high accuracy (AUC range = .81‐.88; Figure 1).”

   Humansdifferentiating Lewy body disease from cognitively unimpaired

   Developing and validating normed scores for cognitive dispersion among older adults

   AAIC 2025 abstract·25 Dec 2025

More on Lewy body disease

1. Cognitive dispersion is associated with cognitive function in humans (b=.41, SE=.05, p<.001).

   “increases in dispersion were most strongly associated with shallower 9-year declines in cognitive performance among comparatively older adults (b=.41, SE=.05, p<.001)”

   Humans9-year

   IS VARIABILITY IN COGNITIVE PERFORMANCE ALWAYS MALADAPTIVE? THE MODERATING ROLE OF SOCIODEMOGRAPHIC FACTORS

   GSA 2024 abstract·31 Dec 2024