CMI5

1. CMI5 raises the risk of cardiometabolic multimorbidity in humans (OR 7.53 (95% CI: 7.30–7.88)).

   “each one-unit increase in CMI5 corresponded to a 6.5-fold higher odds of CMM (OR = 7.53, 95% CI: 7.30–7.88, p < 0.001)”

   Humansmultivariable logistic regression

   Development and validation of CMI5: a novel composite metabolic index for predicting cardiometabolic multimorbidity using routine health check-up data

   Research Square·10 Aug 2026Preprint

2. CMI5 predicts cardiometabolic multimorbidity in humans (AUC 0.904 (95% CI: 0.896–0.912)).

   “In the NHANES internal test set, the CMI5-based model achieved an AUC of 0.904 (95% CI: 0.896–0.912).”

   HumansNHANES internal test set

   Development and validation of CMI5: a novel composite metabolic index for predicting cardiometabolic multimorbidity using routine health check-up data

   Research Square·10 Aug 2026Preprint

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