cfDNA-to-nuclease activity ratio

There is 1 paper on cfDNA-to-nuclease activity ratio in aging research: 1 observational study in people. The newest story, Nov 4, 2026: “Free-floating DNA levels differed across human age groups”.

Biomarker

1 paper studies it1 finding

1 new paper in 30 daysSee all 1 papers on cfDNA-to-nuclease activity ratio

“The cfDNA-to-nuclease activity ratio peaked at 61–80 years and declined thereafter.”
Circulating cell-free DNA and plasma nuclease activity in human agingMechanisms of ageing and development2026doi:10.1016/j.mad.2026.112273
  • Humans1

Associations

1

Chronological age

mixedin humans1

1 study
  1. Chronological age is associated with cfDNA-to-nuclease activity ratio in humans.

    “The cfDNA-to-nuclease activity ratio peaked at 61–80 years and declined thereafter.”

    Humansplasman = 418

    Free-floating DNA levels differed across human age groups

    Mechanisms of ageing and development

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Mechanisms of Ageing and Development

Free-floating DNA levels differed across human age groups

In a cross-sectional study of 418 people aged 7–95, free-floating DNA levels increased across ages 7–80 but were lower at 81–95 than at 61–80.In a cross-sectional study of 418 people aged 7–95, free-floating DNA levels increased across ages 7–80 but were lower at 81–95 than at 61–80.

Cross-sectional · 418 peopleMechanisms