cfDNA concentration–oxidation–nuclease activity composite index

There is 1 paper on cfDNA concentration–oxidation–nuclease activity composite index in aging research: 1 observational study in people. The newest story, Nov 4, 2026: “Free-floating DNA levels differed across human age groups”.

Biomarker

1 paper studies it1 finding

1 new paper in 30 daysSee all 1 papers on cfDNA concentration–oxidation–nuclease activity composite index

“An exploratory composite index integrating cfDNA concentration, oxidation, and nuclease activity increased up to approximately 45 years and subsequently stabilized.”
Circulating cell-free DNA and plasma nuclease activity in human agingMechanisms of ageing and development2026doi:10.1016/j.mad.2026.112273
  • Humans1

Associations

1

Chronological age

upin humans1

1 study
  1. Chronological age is associated with cfDNA concentration–oxidation–nuclease activity composite index in humans.

    “An exploratory composite index integrating cfDNA concentration, oxidation, and nuclease activity increased up to approximately 45 years and subsequently stabilized.”

    Humansplasma

    Free-floating DNA levels differed across human age groups

    Mechanisms of ageing and development

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Mechanisms of Ageing and Development

Free-floating DNA levels differed across human age groups

In a cross-sectional study of 418 people aged 7–95, free-floating DNA levels increased across ages 7–80 but were lower at 81–95 than at 61–80.In a cross-sectional study of 418 people aged 7–95, free-floating DNA levels increased across ages 7–80 but were lower at 81–95 than at 61–80.

Cross-sectional · 418 peopleMechanisms