Cerebral myelin content

1. Unhealthy lifestyle decreases cerebral myelin content in humans (β = -0.24, 95% CI [-0.26 -0.22]).

   “An unhealthy lifestyle (i.e. higher LIBRA score) is significantly associated to a lower cerebral myelin content (β = -0.24, 95% CI [-0.26 -0.22], and p < 0.001).”

   Humansbrainn = 4,653

   The role of modifiable risk factors on the cerebral myelin content and cognition: findings from The Maastricht Study

   GeroScience·20 Mar 2026

More on Unhealthy lifestyle

1. Cerebral myelin content mediates cognitive function in humans (15%).

   “myelin has a partially mediating effect of 15%, indicating that it partly explains the relation between lifestyle-related factors and cognition.”

   Humansin relation between lifestyle-related factors and cognitionn = 4,653

   The role of modifiable risk factors on the cerebral myelin content and cognition: findings from The Maastricht Study

   GeroScience·20 Mar 2026