Cerebral amyloid-beta status classification

1. Multimodal retinal imaging predicts cerebral amyloid-beta status classification in humans (AUC = 0.84, sensitivity = 0.82, specificity = 0.78).

   “Combining HSI and GC-IPL features yielded the best performance (AUC = 0.84; sensitivity = 0.82; specificity = 0.78)”

   HumansPET-confirmed Aβ+ vs Aβ- participantsretinan = 40

   Multimodal Retinal Imaging for the Detection of Early Alzheimer’s Disease: Combining Biochemical, Structural, and Vascular Biomarkers

   Preprints.org·17 Aug 2026Preprint

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