CD4+ EMRA to naive T cell ratio

1. Adverse childhood experiences are associated with CD4+ EMRA to naive T cell ratio in humans (+0.19 standardized value, 95% CI: 0.08, 0.14).

   “women reporting 3+ traumas had a 0.19 higher standardized value of CD4+ EMRA:Naïve (95% CI: 0.08, 0.14)”

   Humans3+ traumas before age 18 compared to nonewhole bloodfemales

   Early Life Trauma and Immune Aging: Evidence of a Biological Threshold in Older Women · GSA 2025 abstract · 31 Dec 2025

Adverse childhood experiences →