CD4 EMRA:naïve ratio

CD4 EMRA:naïve ratio has no effect on cognitive function in humans.

“No significant association was found for the CD4 + EMRA: Naïve ratio.”

Humans6-yearn = 7,444

Peripheral immunosenescence biomarkers and longitudinal cognitive decline: a large population-based study

npj aging·2 Jun 2026

CD4 EMRA:naïve ratio is associated with mortality in humans (15% lower mortality per one-unit increase).

“a one-unit increase in the CD4, EMRA: Naïve ratio was associated with a 15% decrease in mortality among non-Hispanic Black males.”

Humansnon-Hispanic Black malessix yearsmales

The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity

Immunity & ageing : I & A·21 Jun 2025