CD38 NADase activity

Biomarker

1 paper1 finding

  • Cells1

Upstream

1

Senescence-associated secretory phenotype (SASP)

upin cells1

1 study
  1. Senescence-associated secretory phenotype (SASP) increases CD38 NADase activity in cells.

    “increased CD38-NADase activity in non-senescent cells such as endothelial cells or bone marrow derived macrophages”

    Cellsfactors secreted by senescent cells

    The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD⁺ decline

    Biochemical and biophysical research communications8 Apr 2019

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