CD38-expressing cells
1 paper1 finding
- Cells1
Interventions
1TNB-738
no changein cells1
1 study
TNB-738
no changein cells1
TNB-738 has no effect on CD38-expressing cells in cells.
“Due to its silenced IgG4 Fc, TNB-738 did not deplete CD38-expressing cells”
Cellsdue to silenced IgG4 Fc
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
mAbsJan 1, 2022