There are 4 papers on CCL23 in aging research: 4 observational studies in people.
4 papers study it1 more mentions it3 findings
“higher levels of osteoprotegerin (OPG) and chemokine (C-C motif) ligand 23 (CCL23) were cross-sectionally associated with poorer global cognition (beta=-0.205 and beta=-0.148)”
- Humans4
Associations
3Semantic memory
downin humans1
1 study
Semantic memory
downin humans1
CCL23 is associated with semantic memory in humans (cross-sectional, multivariable linear mixed-effect models) (beta=-0.206).
“higher CCL23 was associated with poorer semantic memory (beta=-0.206)”
Humanscross-sectional, multivariable linear mixed-effect modelsn = 642
Inflammatory proteins and cognitive decline in older black adults
Brain : a journal of neurology
Global cognition
downin humans1
1 study
Global cognition
downin humans1
CCL23 is associated with global cognition in humans (cross-sectional, multivariable linear mixed-effect models) (beta=-0.148).
“higher levels of osteoprotegerin (OPG) and chemokine (C-C motif) ligand 23 (CCL23) were cross-sectionally associated with poorer global cognition (beta=-0.205 and beta=-0.148)”
Humanscross-sectional, multivariable linear mixed-effect modelsn = 642
Inflammatory proteins and cognitive decline in older black adults
Brain : a journal of neurology
1RM leg-press strength
downin humans1
1 study
1RM leg-press strength
downin humans1
CCL23 is associated with 1RM leg-press strength in humans (adjusted for age, sex, BMI, cumulative illness rating score and physical performance score) (β= -28.31).
“1RM leg-press had a significant negative relationship with GRO (CXCL2) (β= -18.13, p=0.049), MIG (CXCL9) (β= -13.94, p=0.004), IGF-1 (β= -19.63, p=0.003), CK-BETA 8 (CCL23) (β= -28.31, p=0.018)”
Humansadjusted for age, sex, BMI, cumulative illness rating score and physical performance scoren = 38
Circulating Cytokines and Lower Body Muscle Performance in Older Adults at Hospital Admission
The journal of nutrition, health & aging