BrainAge grey matter PRS

1. BrainAge grey matter PRS is associated with p-Tau217 in humans (p = 0.01, older adults p = 0.007).

   “BrainAge GM PRS was positively associated with p ‐tau 217 levels ( p = 0.01), particularly among the older adults ( p = 0.007).”

   Humanscognitively normal older adultsplasma

   Relationship between Polygenetic Risk Score of BrainAge and plasma biomarkers in the A4/LEARN studies

   AAIC 2025 abstract·23 Dec 2025

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