Brain age gap factor

Brain age gap factor is associated with shared genetic variance in brain age gap in humans (63% of total genetic variance explained).

“All six BAG GWASs loaded onto a single factor, explaining 63% of the total genetic variance.”

HumansSix brain age gap GWASs across 30 cohorts overall

Shared genetic architecture of brain age gap across 30 cohorts worldwide

medRxiv : the preprint server for health sciences·27 Dec 2025Preprint