Blood-brain barrier water permeability-surface area product
Biomarker1 paper3 findings
- Humans1
Upstream
1Type 2 diabetes
upin humans1
1 study
Type 2 diabetes
upin humans1
Type 2 diabetes increases blood-brain barrier water permeability-surface area product in humans (Hedges' g = 1.10, P = 0.001).
Humansin older adults with type 2 diabetes and obesity vs controls
Blood-brain barrier water permeability is elevated in type 2 diabetes and obesity: associations with cognitive function and metabolic markers · Fluids and barriers of the CNS · 22 Jul 2026
Associations
2Executive function
downin humans1
1 study
Executive function
downin humans1
Blood-brain barrier water permeability-surface area product is associated with executive function in humans (P-values < 0.05).
Humanslinear regression adjusted for age and sex
Blood-brain barrier water permeability is elevated in type 2 diabetes and obesity: associations with cognitive function and metabolic markers · Fluids and barriers of the CNS · 22 Jul 2026
HbA1c
upin humans1
1 study
HbA1c
upin humans1
Blood-brain barrier water permeability-surface area product is associated with HbA1c in humans (f2 = 0.28, P = 0.016).
Humansadjusted for age, sex, and statin use
Blood-brain barrier water permeability is elevated in type 2 diabetes and obesity: associations with cognitive function and metabolic markers · Fluids and barriers of the CNS · 22 Jul 2026