Blood-based methylation risk score

1. Blood-based methylation risk score predicts type 2 diabetes in humans (AUC = 0.91).

   “A blood-based methylation risk score based on age-linked CpGs correlates with insulin secretion and improves diabetes classification when combined with genetic risk (AUC = 0.91).”

   Humansblood

   Epigenetic landscapes in human pancreatic islets reveal distinct drivers for adaptation to age and type 2 diabetes

   Nature communications·3 Jun 2026

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