Apparent differences in skeletal muscle capillarization

cross-sectional-area normalization of C:Fi decreases apparent differences in skeletal muscle capillarization in humans (Only an 18% age-group difference remained in type I fibers).

“Normalizing C:Fi to fiber CSA (CFCE) further attenuated or eliminated most differences, with only an 18% difference remaining in type I fibers between age groups.”

HumansC:Fi normalized to fiber cross-sectional areaskeletal musclefemales

Capillary differences with age and muscle fiber type are attenuated by accounting for fiber shape

The FEBS journal·10 Jan 2026