Apparent age-related differences in skeletal muscle capillarization

fiber-shape adjustment of CFPE decreases apparent age-related differences in skeletal muscle capillarization in humans (22–25% differences reduced to 19–20%; ~10–25% relative reduction).

“Adjusting CFPE for fiber shape (CFPESFIadjusted) reduced age-related differences from 22-25% down to 19-20% (~10-25% relative reduction)”

HumansCFPE adjusted for fiber shape using SFIskeletal musclefemales

Capillary differences with age and muscle fiber type are attenuated by accounting for fiber shape

The FEBS journal·10 Jan 2026