What does the research say about antibody response to influenza vaccination?

Antibody response to influenza vaccination

There are 4 papers on antibody response to influenza vaccination in aging research: 3 observational studies in people, 1 review.

4 papers study it14 more mention it3 findings

“distinct IA and inflammatory variables were closely associated with vaccine response in HIV-infected and -uninfected populations”

Metformin

downin humans1

1 study

Metformin is linked with lower antibody response to influenza vaccination in humans (long-term use).
“We noted a diminished response to TIV in the elderly on Metformin”
Humanslong-term uselong-term
Immune response to influenza vaccination in the elderly is altered by chronic medication use
Immunity & ageing : I & AAug 31, 2018

Biological age

no changein humans1

1 study

Biological age was not clearly linked with antibody response to influenza vaccination in HIV-infected and uninfected populations.
“the variable of biological age was not identified in a predictive model as significantly impacting vaccine responses in either group”
Humansin HIV-infected and uninfected populations
Reevaluation of immune activation in the era of cART and an aging HIV-infected population
JCI insightOct 19, 2017

Immune activation and inflammatory variables

mixedin humans1

1 study

Immune activation and inflammatory variables are associated with antibody response to influenza vaccination in HIV-infected and uninfected populations.
“distinct IA and inflammatory variables were closely associated with vaccine response in HIV-infected and -uninfected populations”
Humansin HIV-infected and uninfected populations
Reevaluation of immune activation in the era of cART and an aging HIV-infected population
JCI insightOct 19, 2017