Annual rate of central corneal thickness increase

Older age is associated with annual rate of central corneal thickness increase in humans (β = -0.5; SE = 0.2; 0.20 ± 0.14 versus 0.68 ± 0.08 μm annually).

“with a statistically significant difference between 40s and 70s groups (β = -0.5; SE = 0.2' P = 0.003).”

HumansCommunity-dwelling Japanese adultscorneaApproximately 8 years

Longitudinal Changes in Corneal Thickness over 8 Years: Findings from the National Institute for Longevity Sciences-Longitudinal Study of Aging Population-Based Cohort Study in Japan

Ophthalmology science·19 Jun 2025