Amyloid spatial extent

1. Amyloid spatial extent is associated with Wall Penetration Count in humans (β=0.03, p=0.03, R2=0.18).

   “Wall Penetration Count (β=0.03, p =0.03, R2=0.18) in the NC condition”

   Humanscognitively normal with evidence of amyloid spread (EXT+)n = 32

   Exploring Digital Maze Performance Features Associated with PET Spatial Extent (EXT) in Cognitively Normal Older Adults

   AAIC 2025 abstract·23 Dec 2025

More on Wall Penetration Count

1. Amyloid spatial extent is associated with Speed in humans (β=0.28, p=0.03, R2=0.19).

   “higher EXT% was significantly associated with greater speed (β=0.28, p =0.03, R2=0.19) and Wall Penetration Count (β=0.03, p =0.03, R2=0.18) in the NC condition”

   Humanscognitively normal with evidence of amyloid spread (EXT+)n = 32

   Exploring Digital Maze Performance Features Associated with PET Spatial Extent (EXT) in Cognitively Normal Older Adults

   AAIC 2025 abstract·23 Dec 2025

More on Speed

1. Amyloid spatial extent is associated with speed variability in humans (β=1.69, p=0.01, R2=0.19).

   “higher speed variability (β=1.69, p =0.01, R2=0.19) than the EXT− group”

   Humanscognitively normal

   Exploring Digital Maze Performance Features Associated with PET Spatial Extent (EXT) in Cognitively Normal Older Adults

   AAIC 2025 abstract·23 Dec 2025

More on Speed variability

1. Amyloid spatial extent is associated with Pen Off Page Time in humans (β=4.70, p=0.03, R2=0.13).

   “In the CH condition, the EXT++ group exhibited significantly longer Pen Off Page Time (β=4.70, p =0.03, R2=0.13) and higher speed variability (β=1.69, p =0.01, R2=0.19) than the EXT− group.”

   Humanscognitively normal

   Exploring Digital Maze Performance Features Associated with PET Spatial Extent (EXT) in Cognitively Normal Older Adults

   AAIC 2025 abstract·23 Dec 2025

More on Pen Off Page Time