Amyloid-beta load

Biomarker

1 paper2 findings

  • Humans1

Effects

2

Executive functioning

downin humans1

1 study
  1. Amyloid-beta load impairs executive functioning in humans.

    “Higher Aβ loads across all 4 neocortical regions, cornu ammonis 3, cornu ammonis 1/subiculum, and the entorhinal cortex specifically affected executive functioning.”

    Humans

    Amyloid-Beta Pathology and Cognitive Performance in Centenarians

    JAMA neurology30 Jun 2025

Cognitive function

downin humans1

1 study
  1. Amyloid-beta load impairs cognitive function in humans.

    “Centenarians with no or low Aβ load had significantly higher cognitive performance than centenarians with high Aβ loads.”

    Humans

    Amyloid-Beta Pathology and Cognitive Performance in Centenarians

    JAMA neurology30 Jun 2025

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