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Alpha-smooth muscle actin and collagen-I expression

There is 1 paper on alpha-smooth muscle actin and collagen-I expression in aging research: none in people yet, 1 in animals.

Biomarker

1 paper studies it1 finding

See all 1 papers on alpha-smooth muscle actin and collagen-I expression

  • Animals1

Interventions

1

CB-5083

downin mouse cells1

1 study

  1. CB-5083 decreases alpha-smooth muscle actin and collagen-I expression in mouse cells (also shown by p97 knockdown in mouse and human HSCs).

    “Intervention with the p97 antagonist CB-5083 or the knockdown of p97 reduced the expression of alpha-smooth muscle actin and collagen-I in both mouse or human HSCs.”

    Cellsalso shown by p97 knockdown in mouse and human HSCshepatic stellate cells

    Targeting p97/Valosin-Containing Protein Promotes Hepatic Stellate Cell Senescence and Mitigates Liver Fibrosis

    DNA and cell biology

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