Aging-associated immune cell enrichment

Biomarker

1 paper2 findings

  • Humans1

Interventions

1

High altitude

upin mice1

1 study
  1. High altitude increases aging-associated immune cell enrichment in mice.

    “exhausted T cells, age-associated B cells, and high-aging-score immune cells showed marked enrichment in HAP cohorts, a pattern conserved in mouse models.”

    AnimalsSimulated hypoxic conditionsSimulated 5000-meter altitude

    High altitude-mediated immune remodeling accelerates aging

    Science advances22 Apr 2026

More on High altitude

Associations

1

High altitude

upin humans1

1 study
  1. High altitude is associated with aging-associated immune cell enrichment in humans.

    “aging-associated immune cells (AICs) including exhausted T cells, age-associated B cells, and high-aging-score immune cells showed marked enrichment in HAP cohorts”

    HumansHigh-altitude populations3656-meter and 5070-meter elevations

    High altitude-mediated immune remodeling accelerates aging

    Science advances22 Apr 2026

More on High altitude

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