Age-varying CpG sites
1 paper2 findings
- Humans1
Upstream
1HannumAge
no changein humans1
1 study
HannumAge
no changein humans1
HannumAge has no effect on age-varying CpG sites in humans.
“Established epigenetic clocks (e.g., HannumAge) were significantly enriched for age-associated CpG sites but not for age-varying sites.”
Humans5 yearsn = 135
Aging cell1 Jan 2026
Associations
1Organ-specific pace of aging
mixedin humans1
1 study
Organ-specific pace of aging
mixedin humans1
Age-varying CpG sites are associated with organ-specific pace of aging in humans (925 significant associations).
“identified 925 significant associations between organ-specific pace of aging and longitudinal methylation change rates at age-varying CpG sites.”
Humans5 yearsn = 135
Aging cell1 Jan 2026
Latest
1 in 12 monthsAging Cell
Longitudinal Profiling of DNA Methylation Reveals Age-Varying CpG Sites and Novel Insights Into Aging Heterogeneity
Cohort study of 135 peopleDNA methylation