Age-associated white matter perivascular space volume fraction increase

1. Autism spectrum disorder is associated with age-associated white matter perivascular space volume fraction increase in humans.

   “autistic adults exhibited significantly greater increases in white matter perivascular volume fraction within the left inferior parietal lobule compared with controls.”

   HumansAutistic adults compared with matched controlsleft inferior parietal lobulen = 49

   Altered cerebrospinal fluid-based clearance mechanisms in aging autistic adults

   Research square·20 Apr 2026Preprint

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