Afterhyperpolarization

Biomarker

1 paper1 finding

Animals1

Interventions

Insulin

downin rats1

1 study

Insulin decreases afterhyperpolarization in rats.
“ex vivo insulin also reduced the AHP”
Animalsex vivo
Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging
The journals of gerontology. Series A, Biological sciences and medical sciences6 Feb 2015

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bioRxiv28 Sep

APOE4 alters olfactory neurons across age and sex in mice

Whole-cell recordings in adult and aged humanized mice showed that APOE4 modified pyramidal cell and interneuron properties depending on both age and sex.Whole-cell recordings in adult and aged humanized mice showed that APOE4 modified pyramidal cell and interneuron properties depending on both age and sex.

Preprint: experiments in animalsAPOE

Paper

The Journal of Neuroscience10 Oct

Altered Electrophysiology and Transcriptome of GnRH Neurons in Middle-Aged Female Mice

Experiments in miceMechanisms

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Aging-related adaptations of metabotropic glutamate receptors within the CA3 region of the rat hippocampus

Experiments in rat cellsMechanisms

Paper

The Journals of Gerontology, Series A6 Feb

Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging

Experiments in ratsInsulin

Paper