AD plasma biomarker trajectories
Biomarker1 paper1 finding
- Human trial1
Interventions
1Multidomain lifestyle intervention
no changein humans1Moderate certainty
1 study
Multidomain lifestyle intervention
no changein humans1Moderate certainty
Multidomain lifestyle intervention has no effect on AD plasma biomarker trajectories in humans.
Human trialat-risk individuals without substantial impairment; compared with control2 years
Lifestyle trial found similar Alzheimer’s blood marker changes · medRxiv · 6 Oct 2026 · Preprint
Latest
1medRxivHuman trialPreprint
Lifestyle trial found similar Alzheimer’s blood marker changes
A two-year randomised trial in 1,260 older adults at risk of dementia found no clear evidence that starting blood markers altered cognitive benefits.A two-year randomised trial in 1,260 older adults at risk of dementia found no clear evidence that starting blood markers altered cognitive benefits.