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18F-flutemetamol SUVR

Biomarker

1 paper2 findings

  • Humans1

Upstream

1

White matter hyperintensities

downin humans1

1 study

  1. White matter hyperintensities decrease 18F-flutemetamol SUVR in humans (t102 = 7.8, p < .001).

    “The 18F-flutemetamol standardized uptake value ratio (SUVR) in WMHs was significantly lower than that in NAWM (t102 = 7.8, p < .001).”

    Humansall participantswhite matter hyperintensitiesn = 103

    Accelerated Aging of White Matter in Late-Life Depression: Evidence From ¹⁸F-Flutemetamol Positron Emission Tomography Imaging

    Biological psychiatry. Cognitive neuroscience and neuroimaging7 Apr 2025

Associations

1

Late-life depression

upin humans1

1 study

  1. Late-life depression is associated with 18F-flutemetamol SUVR in humans (Cohen's d = 0.91, p < .001).

    “Compared with HC participants, patients with LLD exhibited higher 18F-flutemetamol SUVR in both NAWM (p < .001, Cohen's d = 0.91) and WMHs (p = .005, d = 0.56)”

    Humanslate-life depressionwhite mattern = 103

    Accelerated Aging of White Matter in Late-Life Depression: Evidence From ¹⁸F-Flutemetamol Positron Emission Tomography Imaging

    Biological psychiatry. Cognitive neuroscience and neuroimaging7 Apr 2025

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