1/CCR×METS-IR

1. 1/CCR×METS-IR raises the risk of cardiometabolic multimorbidity in humans.

   “The "Low CCR and High METS-IR" combination and highest quartile of MRII were consistently linked to elevated CMM risk.”

   Humanshighest quartile

   Cardiometabolic multimorbidity in relation to the metabolic score for insulin resistance and creatinine-to-cystatin C ratio in a middle-aged and aged population

   Frontiers in endocrinology·1 Dec 2025

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