Guodong Wang

Chronic stress accelerates Alzheimer pathology in mice by hyperactivating mTORC1

Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed…Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed Alzheimer model mice.