Xue-lian Wang
Tang Du Hospital1 paperOpenAlex
Papers
Biochemical PharmacologyCells
Sephin1 promotes mitophagy and reduces alpha-synuclein toxicity in Parkinson models
The compound directly binds Prohibitin-2 to activate PINK1-PRKN-dependent clearance of damaged mitochondria, easing motor deficits in transgenic mice.The compound directly binds Prohibitin-2 to activate PINK1-PRKN-dependent clearance of damaged mitochondria, easing motor deficits in transgenic mice.