Yoshiko Takahashi

DNMT3A mutations enhance macrophage migration in cells

Using human stem cell-derived macrophages, a preprint finds DNMT3A mutations derepress bivalent Polycomb target genes and enhance cell migration…Using human stem cell-derived macrophages, a preprint finds DNMT3A mutations derepress bivalent Polycomb target genes and enhance cell migration toward injured tissue.