Helena M. Cochemé
Hammersmith Hospital2 papersORCID 0000-0001-8637-0042OpenAlex
Papers
bioRxivAnimalsPreprint
Dietary restriction activates autophagy through selective oxidation of ATG5
Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation…Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation in mice.
Aging CellModel organisms
Direct AMPK activation extends lifespan across yeast, worms, and flies
Treatment with the direct activator 991 also induced a pro-longevity proteomic profile in mice.Treatment with the direct activator 991 also induced a pro-longevity proteomic profile in mice.