Timothy Edward O’Sullivan
University of California, Los Angeles1 paperORCID 0000-0003-1435-8188OpenAlex
Papers
bioRxivAnimalsPreprint
A distinct p21-driven macrophage senotype accumulates during aging and liver disease
Researchers identified a p53-p21-Cyclin D2 axis that governs senescent macrophages in mice and human liver cirrhosis and can be cleared with…Researchers identified a p53-p21-Cyclin D2 axis that governs senescent macrophages in mice and human liver cirrhosis and can be cleared with senolytics.