Papers by Yi Chen

63 results

  1. Drug Design, Development and Therapy

    GLP-1 agonists linked to lower dementia risk after COVID-19

    GLP-1 receptor agonist initiation was associated with a lower hazard of incident dementia than DPP-4 inhibitors (HR 0.64) in diabetic COVID-19 survivors.GLP-1 receptor agonist initiation was associated with a lower hazard of incident dementia than DPP-4 inhibitors (HR 0.64) in diabetic COVID-19 survivors.

    Cohort study of 25,263 peopleGLP-1 receptor agonists
  2. Clinical Epigenetics

    Biological aging and heart health link to lung disease risk

    A study of 181,955 UK Biobank participants linked accelerated biological aging and lower cardiovascular health to higher risks of chronic respiratory diseases.A study of 181,955 UK Biobank participants linked accelerated biological aging and lower cardiovascular health to higher risks of chronic respiratory diseases.

    Study in peoplePopulations
  3. Cell Reports

    Myelin lipid buildup links to lysosomal defects in mice

    Profiling lysosomal fractions from mouse cortex from 3 to 24 months revealed an accumulation of myelin-derived glycosphingolipids that was most pronounced in microglia.Profiling lysosomal fractions from mouse cortex from 3 to 24 months revealed an accumulation of myelin-derived glycosphingolipids that was most pronounced in microglia.

    Experiments in miceLysosome